Dog

Neonatal interstitial lung disease is a genetic disease affecting the pulmonary system and causing lethal hypoxic respiratory failure in the first weeks of life. Other symptoms include lethargy, refusal to suckle and breathing difficulties ('dyspnea' or tachypnea).

Gangliosidosis is a genetic defect that causes the storage of GM1 gangliosides in various tissues. The clinical signs of the disease are progressive neurological dysfunction and growth retardation.

Dogs with POAG have elevated intraocular pressure that can lead to vision loss. Symptoms of this condition include eye pain, excessive blinking and tearing.

Postoperative hemorrhage is a genetic disorder affecting platelet function. Symptoms are related to abnormal coagulation and include heavy bleeding during surgery or trauma. The first clinical signs may appear as early as birth.

Inflammatory pulmonary disease is a genetic disease affecting the immune system. Symptoms include fever, cough, difficulty breathing and foamy vomiting. The first clinical signs appear at birth.

Centronuclear myopathy is a genetic disease affecting the muscles and characterized by progressive muscle atrophy and exercise intolerance. The first clinical signs appear around 6 months of age.

Exfoliative cutaneous lupus erythematosus is a genetic skin disease whose symptoms are erythema, scabbing, alopecia and scaling of the skin. The first signs of the disease usually appear during the first year.

Bilateral deafness and vestibular dysfunction is a genetic disease affecting the nervous system. The clinical signs of this pathology are deafness, head tilt, circular movements and lack of coordination of the limbs as well as abnormal eye movements. The first symptoms (deafness) usually appear at the age of 3 weeks.

Hereditary ataxia is a genetic disease causing a degeneration of the nerve cells. The symptoms of this pathology are progressive motor disorders leading to an inability to walk as well as a proprioceptive deficit of the hind limbs. The first clinical signs usually appear between 4 and 19 months of age.

Mitochondrial fission encephalopathy is a genetic disease of the nervous system. Bullmastiffs with MFE show a variety of symptoms such as ataxia, visual impairment, progressive gait abnormalities and behavioral abnormalities. The first clinical signs are usually observed around 6 months of age.