Dog

Cyclic neutropenia is a stem cell disease resulting in cyclic variation in the number of circulating neutrophils. The clinical signs of cyclic neutropenia are fever, diarrhoea, joint pain and respiratory, eye and skin infections. 

Centronuclear myopathy is a condition characterised by a generalised loss of tone, muscle control, exercise intolerance and clumsy gait. This myopathy usually manifests itself in puppies at the age of 2-5 months.

This test is also recommended for Labradoodle as part of the breeding program established by the Flemish government (see official program).

Scott syndrome is characterised by an increased tendency to bleed due to altered coagulation activity.

This test is also recommended for Chinese Crested Dog as part of the breeding program established by the Flemish government (see official program).

Copper toxicosis is characterised by an accumulation of copper in the liver and other organs leading to chronic hepatitis and cirrhosis of the liver which may progress to necrosis.

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Dystrophic epidermolysis bullosa is caused by an abnormality in collagen synthesis and is characterised by the presence of blisters at the dermal-epidermal junction leading to epidermal detachment. Affected puppies show skin lesions and ulcers.

Amelogenesis imperfecta (AI) is a genetic disorder affecting tooth enamel, causing it to be thin, brittle, or poorly mineralized. In Akitas, a recessive variant in the ACP4 gene has been identified, leading to hypoplastic AI due to an abnormal protein structure. The carrier frequency in Akitas is 22%. While AI cannot be cured, genetic testing can help manage breeding programs and improve dental care strategies.