Dog

Ichthyosis type 2 is a skin condition caused by keratin dysfunction. The skin of affected dogs is dry, thick, scaly with large skin scales. 

In addition to the genetic test available for this form, a specific test is also available for ichthyosis type 1.

Ichthyosis is a skin condition caused by keratin dysfunction. The skin of affected dogs is dry, thick, scaly with large skin scales. 

In addition to the genetic test available for this form, a specific test is also available for ichthyosis type 2.

Imerslund-Gräsbeck syndrome is characterised by malabsorption of vitamin B12 (cobalamin). The first symptoms appear around 6 to 12 weeks. The clinical signs are due to the lack of cobalamin which causes megaloblastic anaemia and neurological symptoms.

Imerslund-Gräsbeck syndrome is characterised by malabsorption of vitamin B12 (cobalamin). The first symptoms appear around 6 to 12 weeks. The clinical signs are due to the lack of cobalamin which causes megaloblastic anaemia and neurological symptoms.

Junctional epidermolysis bullosa (JEB) is a recessive genetic disease of the skin and mucous membranes in which the epidermal layer is separated from the skin.

Juvenile laryngeal paralysis and polyneuropathy also known as polyneuropathy with ocular abnormalities and neuronal vacuolation (POANV) is a neurological defect seen in Black Russian Terriers and Rottweilers where the disease is known as neuronal vacuolation and neuronal vacuolation and spinocerebellar degeneration (NVSD). Signs of disease include early onset of laryngeal paralysis, microphthalmia (small eyes), cataract and muscle weakness. The disease is progressive and affected animals die or are euthanised

L-2-hydroxyglutaric aciduria is a genetic disease of the nervous system. The clinical signs are high levels of L-2-hydroxyglutaric acid in urine and plasma, seizures, wobbly gait, ataxia, tremors and muscle stiffness and usually appear from 6 months of age.

Myotonia congenita is a genetic disorder characterised by delayed skeletal muscle relaxation after contraction. The clinical signs are a stiff gait and hypertrophy of the skeletal muscles.

Landseers with Ullrich-type muscular dystrophy show general muscle weakness. The first symptoms appear in the first months of life, and these dogs are euthanised or die before the age of two.

Mucopolysaccharidosis VII is a lysosomal storage disease characterised by the accumulation of glycosaminoglycans in cells causing permanent cell damage. The first clinical signs are a shortened face, protruding ears and a broad chest. The condition progresses to corneal opacification, reduced growth, locomotor disorders, cardiac abnormalities and tracheal narrowing.