Dog

Ichthyosis, also known as autosomal recessive congenital ichthyosis (ARCI), is a non-inflammatory skin disease characterised by flaky or scaly skin. Clinical signs appear in puppies as early as 1 to 2 weeks of age. Affected dogs have a sticky, oily, yellowish substance around the eyes and ears. In severe cases, puppies are usually euthanised.

Familial nephropathy is a kidney disease with progressive destruction of both kidneys. The first symptoms are excessive water consumption, weight loss, reduced appetite and vomiting.

Benign familial juvenile epilepsy is a disease in which clinical signs appear between 5 and 12 weeks of age. Affected dogs exhibit convulsions characterised by generalised tremors, ataxia and stiffness.

Neonatal ataxia, also known as Bandera syndrome, is caused by a genetic mutation that alters the part of the nervous system that controls coordination and movement. Symptoms of neonatal ataxia include falling and inability to walk.

This test is also recommended for Havanese as part of the breeding program established by the Flemish government (see official program).

Cerebellar abiotrophy is a neurodegenerative disease. Affected puppies show a variety of symptoms including loss of balance and an asymmetric gait with an inability to regulate speed and amplitude of movement. 

Puppies with dry eye/curly coat syndrome have keratoconjunctivitis sicca in the eyes, a curly coat, and are generally smaller than their peers. The footpads are hyperkeratinised with abnormal claw growth.

L'insuffisance d'Adhérence Leucocytaire est une anomalie du système immunitaire. En raison de la mutation, les leucocytes ne détruisent pas les bactéries et les virus conduisant à la mort des chiots atteints.

Leukocyte Adhesion Deficiency is an abnormality of the immune system. Due to the mutation, the leukocytes do not destroy bacteria and viruses leading to the death of affected puppies.

This cardiomyopathy leads to death without apparent cause at around 6-8 weeks of age in the Belgian Shepherd. Symptoms of this condition vary from individual to individual and include: vomiting, dyspnoea, enlarged heart, difficulty in locomotion, tremors.

Congenital myasthenic syndrome is caused by a malfunction in the transmission of nerve signals to the muscle, with symptoms usually appearing between 6 and 12 weeks of age. Affected puppies show generalised skeletal muscle weakness and fatigue, usually induced by exercise.

This test is also recommended for Labradoodle as part of the breeding program established by the Flemish government (see official program).