The SLC6A3 PolyA(22) mutation, found in some Belgian Malinois, is linked to increased activity, stress-related behaviors, and episodic behavioral changes. Dogs with this mutation may show higher locomotor activity and sensitivity to environmental stress. Breeders should consider genetic testing for this mutation when selecting for behavior traits, while vets can use it to assess and manage behavior, especially aggression and stress. Identifying this mutation can aid in more targeted behavior management strategies.
