The SLC6A3 PolyA(22) mutation, found in some Belgian Malinois, is linked to increased activity, stress-related behaviors, and episodic behavioral changes. Dogs with this mutation may show higher locomotor activity and sensitivity to environmental stress. Breeders should consider genetic testing for this mutation when selecting for behavior traits, while vets can use it to assess and manage behavior, especially aggression and stress. Identifying this mutation can aid in more targeted behavior management strategies.

This test is also available for Border Collies, in which the SLC6A3 PolyA(22) variant has been identified. However, no association between this variant and aggression or seizures has been demonstrated to date in this breed.

Transmission

Breed

Belgian Shepherd, Border Collie