Dog

Each dog has its own DNA signature. It is a sort of genetic identity card containing 22 microsatellites recommended by the International Society for Animal Genetics (ISAG). Progenus is accredited ISO17025 for this test.

This package includes the mandatory tests defined by the Flemish breeding program for Airedale terrier:

Progressive retinal atrophy (DOG-PRA-CRD4), Degenerative myelopathy type 2 (DOG-DM2) and Fatal neonatal interstitial lung disease (DOG-LUNG).

Imerslund-Gräsbeck syndrome is characterised by malabsorption of vitamin B12 (cobalamin). The first symptoms appear around 6 to 12 weeks. The clinical signs are due to the lack of cobalamin which causes megaloblastic anaemia and neurological symptoms.

Hypocatalasia (or acatalasemia) is a rare genetic disorder caused by a mutation in the CAT gene, leading to a severe deficiency of catalase. This enzyme normally protects tissues against oxidative stress. The c.979G>A (p.Ala327Thr) mutation was first identified in a Beagle colony and subsequently detected in pet Beagles. A homozygous dog notably developed oral cavity gangrene with tooth loss at a young age. The disease may remain clinically silent for a long time, which highlights the importance of genetic screening in breeding dogs.
This test is also recommended for the Basset Hound as part of the Flemish government breeding program (see the official program).

Multifocal CMR3 retinopathy is a genetic disease that causes multiple tears and detachments of the retina. In mild cases, the dog often shows no vision problems despite the abnormal appearance of the retina.

Craniomandibular osteopathy (CMO) is a bone disease affecting young dogs, usually between 4 and 8 months of age.
It appears as swelling of the jaw, pain, difficulty opening the mouth, fever, and loss of appetite. Excessive bone growth mainly affects the mandible and skull, and sometimes the long bones.
The mutation may be present without causing visible symptoms, due to its variable expression and incomplete penetrance.

This test is also recommended for the American Staffordshire Terrier as part of the breeding program of the Flemish government (see the official program).

This panel includes the specific tests to be performed for the Black Russian Terrier: hyperuricosuria (DOG-HUU) and Juvenile Laryngeal Paralysis and Polyneuropathy (DOG-JLPPTNR)

This panel includes the specific tests to be performed for Staffordshire Bull Terriers: cataract (DOG-HSF4-T) and L2 hydroxiglutaric aciduria (DOG- L-2-HGA).

This package includes the mandatory tests defined by the Flemish breeding program for Welsh Corgi Pembroke: Degenerative myelopathy 2 (DOG-DM2), Exercise-induced collapse (DOG-EIC) and Von Willebrand disease type 1 (DOG-VWD1). The Flemish breeding program also recommends the test (DOG-PRA-RCD3).

This package includes the mandatory tests defined by the Flemish breeding program for Welsh Corgi Cardigan: Coat color merle (DOG-LOCUS-M) and Degenerative myelopathy 2 (DOG-DM2). The Flemish breeding program also recommends the tests included in our package DOG-CORGI-C-VL+.