Craniomandibular osteopathy (CMO) is a bone disease affecting young dogs, usually between 4 and 8 months of age. It appears as swelling of the jaw, pain, difficulty opening the mouth, fever, and loss of appetite. Excessive bone growth mainly affects the mandible and skull, and sometimes the long bones. The mutation may be present without causing visible symptoms, due to its variable expression and incomplete penetrance.
This test is also recommended for the American Staffordshire Terrier as part of the breeding program of the Flemish government (see the official program).
Transmission
Autosomal dominant with incomplete penetrance
Breed
American Staffordshire Terrier (Amstaff), Cairn Terrier, West Highland White Terrier, Scottish Terrier
