Familial nephropathy (COL4A4: c.115A>T)
Familial nephropathy (FN) is a genetic disease affecting the kidneys. Dogs with this disorder develop progressive kidney failure leading to death. The first symptoms usually appear between 6 months and 2 years of age and include excessive water consumption, weight loss, decreased appetite, diarrhea and vomiting.
This test is also recommended for English Springer Spaniel as part of the breeding program established by the Flemish government (see official program).
Transmission
Autosomal recessiveBreed
English Cocker Spaniel, English Springer Spaniel



