Pituitary dwarfism (LHX3: c.545_547dup)

€49.85
Test code: DOG-PD
Analysis timeframe: 10 working days
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Pituitary dwarfism in dogs is a hereditary endocrine disorder linked to abnormal development of the pituitary gland, resulting in insufficient production of several essential hormones, including growth hormone. Affected puppies initially show normal growth, followed by a marked slowdown, leading to proportionate dwarfism. This hormonal deficiency is often associated with characteristic skin abnormalities, such as bilateral symmetrical alopecia and persistence of the juvenile coat. Secondary dermatological complications may occur, including skin infections and pigmentation disorders. Associated anatomical abnormalities, particularly at the atlanto-axial junction, may lead to neurological signs.

 

Transmission

Autosomal recessive

Breed

German Shepherd

Gene

LHX3: c.545_547dup