Stargardt disease (ABCA4: c.4176insC)
Stargardt disease 1 is a genetic retinal disorder observed in the Labrador Retriever. It causes progressive degeneration of photoreceptors, initially affecting the visual streak and later the entire retina. Affected dogs show reduced vision, noticeable in both daylight and low-light conditions, with abnormal pupillary reflexes. The progression is slow, and most dogs retain some vision throughout their lives. Heterozygous carriers may show mild retinal abnormalities without obvious visual impairment.
This test is also recommended for the German Shorthaired Pointer as part of the breeding program of the Flemish government (see the official program).
Transmission
Autosomal recessiveBreed
German Pointer, Labrador Retriever



