Dog

Autoinflammatory Shar-Pei Disease (AISD) is a genetic disorder characterized by recurrent episodes of fever and inflammation with no known cause. The most common symptoms are fever, arthritis, vesicular hyaluronosis, otitis and amyloidosis.

Dogs with photoreceptor dysplasia appear normal up to 10 months old but develop vision problems by 3 years, such as slow pupillary reflexes and difficulty seeing in familiar places. Fundus abnormalities include vessel loss and retinal thinning, leading to eventual blindness before age five.

Factor VII deficiency is a genetic disorder affecting blood clotting. Symptoms are related to mild blood clotting disorders such as bleeding and bruising.

Rod-cone dysplasia type 3 is one of the various forms of progressive retinal atrophy (PRA). This mutation leads to a progressive loss of night vision and subsequently daytime vision until total blindness.

Achromatopsia, also known as Early Cone Degeneration, causes daytime blindness due to degeneration of the retinal cones. It can be diagnosed in the first few weeks of a puppy's life. Affected dogs become colour blind and photophobic.

Achromatopsia, also known as Early Cone Degeneration, causes daytime blindness due to degeneration of the retinal cones. It can be diagnosed in the first few weeks of a puppy's life. Affected dogs become colour blind and photophobic.

Acral Mutilation Syndrome is characterised by sensory neuropathy of the paws causing insensitivity to pain in the distal parts. Affected dogs usually show signs of extremity self-mutilation. Proprioception, motor skills and reflexes remain intact.

Ichthyosis, also known as autosomal recessive congenital ichthyosis (ARCI), is a non-inflammatory skin disease characterised by flaky or scaly skin. Clinical signs appear in puppies as early as 1 to 2 weeks of age. Affected dogs have a sticky, oily, yellowish substance around the eyes and ears. In severe cases, puppies are usually euthanised.

Familial nephropathy is a kidney disease with progressive destruction of both kidneys. The first symptoms are excessive water consumption, weight loss, reduced appetite and vomiting.

Benign familial juvenile epilepsy is a disease in which clinical signs appear between 5 and 12 weeks of age. Affected dogs exhibit convulsions characterised by generalised tremors, ataxia and stiffness.