Cat

The mutation of the MLPH gene leads to a dilution of the intensity of the coat colour. The black coat becomes blue, the orange becomes cream and the chocolate coat is diluted to lilac.

Cats carrying the DW (white dominant) allele have a white coat. This mutation is also associated with hearing problems and deafness. Cats with two mutated alleles are more likely to have hearing problems than cats with one allele.

The albino mutation is a rare mutation that produces a white coat and blue eyes, and is recessive to the colorpoint mutations (see CAT-COLOPOINT test).

Different mutations in the FGF5 gene produce long hair in cats. Progenus tests for mutation 4 which is present in many breeds.

A mutation in the KRT71 gene is responsible for the virtual absence of hair in the Sphynx. This genetic alteration disrupts normal hair production, leading to almost total loss of coat.

The Devon Rex's distinctive curly coat is the result of a genetic mutation in the KRT71 gene, which is essential for hair formation. This mutation causes an alteration in the structure of the hair, giving the Devon Rex its characteristic appearance, with tight curls and a unique texture. All Devon Rexes analysed have two copies of this mutation, which means that it is fixed in the breed and determines the curly phenotype. This mutation is specific to the Devon Rex and has not been observed in other rexoid breeds or hairless varieties, highlighting its uniqueness within the breed.