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Progressive retinal atrophy is an inherited eye disease characterized by bilateral degeneration of the photoreceptor cells of the retina resulting in progressive vision loss leading to total blindness. Other mutations can cause progressive retinal atrophy. 

Von Willebrand disease is a condition that causes excessive bleeding due to a lack or reduced level of von Willebrand factor (vWF), a blood clotting protein. 

Von Willebrand disease is a condition that causes excessive bleeding due to a deficiency or reduced levels of von Willebrand factor (vWF), a blood clotting protein.

This mutation is found in the Chinese Crested dog, but homozygous dogs do not appear to show clinical signs of bleeding disorders.

Hypocatalasia (or acatalasemia) is a rare genetic disorder caused by a mutation in the CAT gene, leading to a severe deficiency of catalase. This enzyme normally protects tissues against oxidative stress. The c.979G>A (p.Ala327Thr) mutation was first identified in a Beagle colony and subsequently detected in pet Beagles. A homozygous dog notably developed oral cavity gangrene with tooth loss at a young age. The disease may remain clinically silent for a long time, which highlights the importance of genetic screening in breeding dogs.
This test is also recommended for the Basset Hound as part of the Flemish government breeding program (see the official program).

Exercise induced collapse is a neuromuscular disorder characterised by muscle weakness, incoordination and life-threatening collapse after intense exercise. Five to fifteen minutes of intense exercise causes dogs with this syndrome to develop a staggering gait and loss of control of the hind limbs. The episode may extend to all four limbs. Collapsing episodes usually last 5-10 minutes, and after 30 minutes there is often a full recovery, but episodes are sometimes fatal. This test is patented and subcontracted to the patent holding laboratory.

The amber gene causes kittens to gradually change their coat colour from black at birth to an amber colour. This change is mainly observed during the first year. The coat colour of the cat also depends on complex interactions with other genes.

Cone-rod dystrophy 2 is a form of progressive retinal atrophy characterised by an early, severe and rapidly progressive loss of cone function accompanied by a progressive loss of rods.

Pyruvate kinase deficiency is a haemolytic anaemia that reduces the longevity of erythrocytes (red blood cells). In the domestic cat, pyruvate kinase deficiency has a wide variability in the onset and severity of clinical symptoms. Symptoms of this anaemia may include severe lethargy, weakness, weight loss, jaundice and abdominal enlargement.

This pack includes the recommended tests defined by the Flemish breeding program for Golden Retriever: neuronal ceroid lipofuscinosis type 5 (DOG-NCL5GR), degenerative myelopathy type 2 (DOG-DM2), and ichthyosis type 2 (DOG-ICHGR-2).

The Flemish breeding program also requires the tests included in our DOG-RETRIVER-VL pack.

Multifocal retinopathy is an eye disease with symptoms appearing between 11 and 16 weeks of age. Affected dogs have multiple circular areas of retinal detachment. Fluid accumulates under the detached retina, resulting in blistering of the eye. The disease progresses slowly and does not usually lead to blindness.