Search results for: 'DOG-PRA-PRCD'

This pack includes the recommended tests defined by the Flemish breeding program for Maine coon: Drug sensitivity (CAT-MDR1), Polycystic kidney disease (CAT-PKD), Progressive retinal atrophy (CAT-PRA-RDAC) and Spinal muscular atrophy (CAT-SMA).

Postoperative hemorrhage is a genetic disorder affecting platelet function. Symptoms are related to abnormal coagulation and include heavy bleeding during surgery or trauma. The first clinical signs may appear as early as birth.

The E locus or extension refers to a mutation in the MC1R gene. For this test code, the mutation being tested is the e^2 mutation. In the Australian Cattle Dog, dogs with two copies of the e^1 or e^2 alleles or one copy of each allele will have a cream coat. For the e^1 allele and other breeds, see the following link: DOG-LOCUS-E.

Mutated dogs are naked except for the tips of the legs, the tail and the top of the head. Some dogs have very abnormal teeth, many of which are missing. In the Chinese Crested Dog, mating hairless individuals can lead to a reduction in litter size, as the presence of a double dose of the mutation in homozygous puppies results in prenatal mortality.

Dogs with photoreceptor dysplasia appear normal up to 10 months old but develop vision problems by 3 years, such as slow pupillary reflexes and difficulty seeing in familiar places. Fundus abnormalities include vessel loss and retinal thinning, leading to eventual blindness before age five.

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Progressive retinal atrophy (IFT122) is a genetic disease of the Finnish Lapphund that causes gradual degeneration of the retina, primarily affecting night vision. Early signs include night blindness and diffuse tapetal hyperreflectivity, detectable through an ophthalmologic examination. The disease generally progresses slowly, and some dogs may retain partial vision at an advanced age.

This test is also recommended for the Finnish Lapphund as part of the breeding program implemented by the Flemish government (see official program).

Cone-rod dystrophy 1 is a form of progressive retinal atrophy characterised by an early, severe and rapidly progressive loss of cone function accompanied by a progressive loss of rods.

Cone-rod dystrophy 2 is a form of progressive retinal atrophy characterised by an early, severe and rapidly progressive loss of cone function accompanied by a progressive loss of rods.

Gangliosidosis is a genetic defect that causes the storage of GM1 gangliosides in various tissues. The clinical signs of the disease are progressive neurological dysfunction and growth retardation