Search results for: 'DOG-PRA-PRCD'

This pack includes the recommended tests defined by the Flemish breeding program for l'Australian Mist: l'hypokaliémie (CAT-HK), Pyruvate kinase deficiency (CAT-PKDEF), Gangliosidosis type 2 (CAT-GM2-BUR) and Progressive retinal atrophy (CAT-PRA-RDAC).

This pack includes the recommended tests defined by the Flemish breeding program for Maine coon: Drug sensitivity (CAT-MDR1), Polycystic kidney disease (CAT-PKD), Progressive retinal atrophy (CAT-PRA-RDAC) and Spinal muscular atrophy (CAT-SMA).

Progressive retinal atrophy (PRA) linked to the AIPL1 gene is a hereditary genetic disease described in Persian cats. It causes rapid degeneration of retinal photoreceptors, with the onset of cell loss as early as 5 weeks of age and severe involvement by 16 weeks. The first clinical signs include an early decrease in night vision, followed by loss of daytime vision.

This test is also recommended for the Exotic Shorthair as part of the Flemish government breeding program (see the official program).

Postoperative hemorrhage is a genetic disorder affecting platelet function. Symptoms are related to abnormal coagulation and include heavy bleeding during surgery or trauma. The first clinical signs may appear as early as birth.

The E locus or extension refers to a mutation in the MC1R gene. For this test code, the mutation being tested is the e^2 mutation. In the Australian Cattle Dog, dogs with two copies of the e^1 or e^2 alleles or one copy of each allele will have a cream coat. For the e^1 allele and other breeds, see the following link: DOG-LOCUS-E.

Dogs with photoreceptor dysplasia appear normal up to 10 months old but develop vision problems by 3 years, such as slow pupillary reflexes and difficulty seeing in familiar places. Fundus abnormalities include vessel loss and retinal thinning, leading to eventual blindness before age five.

Mutated dogs are naked except for the tips of the legs, the tail and the top of the head. Some dogs have very abnormal teeth, many of which are missing. In the Chinese Crested Dog, mating hairless individuals can lead to a reduction in litter size, as the presence of a double dose of the mutation in homozygous puppies results in prenatal mortality.

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

The curly coat is caused by a mutation in the Keratin-71 (KRT71) gene. The test can be performed for any breed but is particularly relevant for the following breeds: Airedale Terrier, Bichon Frise, Havanese, Maltese, Border Collie, Chesapeake Bay Retriever, Chihuahua, Dachshund, Leonberger, Portuguese Water Dog, Welsh Terrier, Wire Fox Terrier. This test is not valid for the Golden Retriever.

Scott syndrome is characterised by an increased tendency to bleed due to altered coagulation activity.

This test is also recommended for Chinese Crested Dog as part of the breeding program established by the Flemish government (see official program).