Progressive Retinal Atrophy - MERTK
Progressive Retinal Atrophy (PRA) is a genetic disease observed in dogs, particularly in the Swedish Vallhund breed. This disease is characterized by the multifocal appearance of red and brown discoloration in the ocular fundus, followed over time by thinning of the retina. It progresses in three stages: in Stage 2, there is a gradual loss of function of both rod and cone photoreceptors, measured by electroretinography. Night blindness occurs first at the end of Stage 2, followed by decreased daytime vision in Stage 3. Histological examinations confirm the loss of photoreceptor cells at Stage 3.
This test is also recommended for the Chinese Crested Dog as part of the breeding program established by the Flemish government (see official program).
Transmission
Autosomal recessiveBreed
Chinese crested dog, Swedish Vallhund



