Progressive retinal atrophy (AIPL1: c.577C>T)
Progressive retinal atrophy (PRA) linked to the AIPL1 gene is a hereditary genetic disease described in Persian cats. It causes rapid degeneration of retinal photoreceptors, with the onset of cell loss as early as 5 weeks of age and severe involvement by 16 weeks. The first clinical signs include an early decrease in night vision, followed by loss of daytime vision.
This test is also recommended for the Exotic Shorthair as part of the Flemish government breeding program (see the official program).
Transmission
Autosomal recessiveBreed
Exotic Shorthair, Persian



