Search results for: 'WA 0859 3970 0884 RAB Renovasi Rumah 2 Lantai Lebar 5 Meter Berpengalaman Tempel Sleman'

Neuronal ceroid lipofuscinosis is a genetic defect characterised by progressive behavioural changes, hyperactivity, dementia, aggression, loss of coordination, ataxia, delayed postural responses, blindness and slow responses to pupillary light.

Neural ceroid-lipofuscinosis is a genetic defect characterised by progressive behavioural changes, hyperactivity, dementia, aggression, loss of coordination, ataxia, delayed postural responses, blindness and slow responses to pupillary light.

Progressive retinal atrophy (PRA1) is a genetic disease characterised by the degeneration of rod photoreceptors in the eye. The first symptoms of vision loss appear between the ages of 4 and 6.

Gangliosidosis is characterised by muscle tremors and loss of motor control. The first symptoms are observed at around 6-8 weeks of age and start with slight tremors that result in feeding difficulties and lack of coordination.

This test is also recommended for Bombay as part of the breeding program established by the Flemish government (see official program).

GM2 gangliosidosis is an inherited disease caused by a deficiency of the enzyme β-hexosaminidase, leading to the accumulation of GM2 gangliosides in the nervous system.
In Korat cats, the first signs appear as early as 4 to 6 weeks of age with fine head tremors.
The disease progresses quickly with coordination problems, falls, and abnormal gait.
Affected kittens show severe deterioration over the following months.
Sadly, the outcome is fatal before 8 months of age.

 

Ichthyosis type 2 is a skin condition caused by keratin dysfunction. The skin of affected dogs is dry, thick, scaly with large skin scales. 

In addition to the genetic test available for this form, a specific test is also available for ichthyosis type 1.

Degenerative myelopathy is a neurodegenerative disease that progresses slowly and has a late onset (8 years or more). The initial clinical sign is characterised by hind limb ataxia. As the disease progresses, the frequently observed asymmetric weakness rises to affect the thoracic limbs, resulting in paraplegia. The majority of DM2/DM2 animals will not develop symptoms, however, elimination of these animals from breeding patterns reduces the genetic variability of the breed, which is why Progenus does not recommend this test.

Polyneuropathy type 1 (LNP21) is a progressive neuromuscular disease characterised by generalised weakness, hypotonia, laryngeal paralysis and muscle atrophy, particularly of the hind limbs. The age of onset of symptoms can vary between 1 and 11 years.

Spongy degeneration with cerebellar ataxia 2 is a neurodegenerative disorder of the cerebellum. Affected puppies show ataxia with motor disorders, muscle spasms and loss of balance. Following the progression of symptoms, puppies are usually euthanised before 4 months of age.

L-2-hydroxyglutaric aciduria is a genetic disease of the nervous system. The clinical signs are high levels of L-2-hydroxyglutaric acid in urine and plasma, seizures, wobbly gait, ataxia, tremors and muscle stiffness and usually appear from 6 months of age.