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Achromatopsia, also known as Early Cone Degeneration, causes daytime blindness due to degeneration of the retinal cones. It can be diagnosed in the first few weeks of a puppy's life. Affected dogs become colour blind and photophobic.

Leukocyte Adhesion Deficiency is an abnormality of the immune system. Due to the mutation, the leukocytes do not destroy bacteria and viruses leading to the death of affected puppies.

This package includes the mandatory tests defined by the Flemish breeding program for German Shepherd: Degeneratieve myelopathie 2 (DOG-DM2) and Scott Syndrome (DOG-CSS).

The Flemish breeding program also recommends the tests included in our DOG-BGALL-VL+ pack.

Mucopolysaccharidosis VII is a lysosomal storage disease characterised by the accumulation of glycosaminoglycans in cells causing permanent cell damage. The first clinical signs are a shortened face, protruding ears and a broad chest. The condition progresses to corneal opacification, reduced growth, locomotor disorders, cardiac abnormalities and tracheal narrowing.

Dwarfism is a slowing of growth. Pituitary dwarfism in German Shepherds produces perfectly proportioned but much smaller dogs. It is caused by a dysfunction of the pituitary gland which reduces the plasma concentrations of growth and thyroid hormones. This hormonal alteration usually results in malformations of the genitalia. These dogs can lead a normal life if they receive appropriate hormonal treatment.

This pack includes the recommended tests defined by the Flemish breeding program for German Shepherd:

Colley eye anomaly (DOG-CEA), type 3 leukocyte adhesion deficiency (DOG-CLAD3), drug sensitivity (DOG-MDR1), progressive retinal atrophy (DOG-PRA-PRCD), and pituitary dwarfism (DOG-PD).

The Flemish breeding program also requires the tests included in our DOG-BGALL-VL pack.

Locus Em or melanin mask causes the black mask on the dog's face. This allele is dominant because only one copy is needed to express the mask phenotype. The mask can be tested for in any breed, but is most commonly found in the breeds listed below.

Malignant hyperthermia, also known as canine stress syndrome, is a potentially fatal genetic disorder. The clinical signs of malignant hyperthermia are extreme muscle contractions, increased heart rate and fever. These symptoms are triggered by certain anaesthetics such as halothane, but also by intense exercise and certain foods. Malignant hyperthermia can be tested for in any breed, but is most commonly found in the breeds listed below.

Pituitary dwarfism in dogs is a hereditary endocrine disorder linked to abnormal development of the pituitary gland, resulting in insufficient production of several essential hormones, including growth hormone. Affected puppies initially show normal growth, followed by a marked slowdown, leading to proportionate dwarfism. This hormonal deficiency is often associated with characteristic skin abnormalities, such as bilateral symmetrical alopecia and persistence of the juvenile coat. Secondary dermatological complications may occur, including skin infections and pigmentation disorders. Associated anatomical abnormalities, particularly at the atlanto-axial junction, may lead to neurological signs.

 

Hyperuricemia, also known as hyperuricosuria, is a genetic defect causing high levels of uric acid in the urine. The clinical signs of the disease are stones in the bladder or kidneys. HUU can be tested for in any breed, but is most commonly found in the breeds listed below.