Search results for: 'DOG-PRA-PRCD'

Spongy degeneration with cerebellar ataxia 1 is a neurodegenerative disorder of the cerebellum. Affected puppies show ataxia with motor disorders, muscle spasms and loss of balance. Following the progression of symptoms, puppies are usually euthanised before 4 months of age.

Spongy degeneration with cerebellar ataxia 2 is a neurodegenerative disorder of the cerebellum. Affected puppies show ataxia with motor disorders, muscle spasms and loss of balance. Following the progression of symptoms, puppies are usually euthanised before 4 months of age.

Fucosidosis is a lysosomal storage disorder that causes the accumulation of proteins and lipids in organs and mainly in brain tissue, resulting in neurological symptoms. Affected animals show coordination and behavioural disorders, blindness and deafness. The first symptoms appear at around 18 months of age with a progression leading to the death of the animal.

Hereditary ataxia is a genetic disease causing a degeneration of the nerve cells. The symptoms of this pathology are progressive motor disorders leading to an inability to walk as well as a proprioceptive deficit of the hind limbs. The first clinical signs usually appear between 4 and 19 months of age.

Bilateral deafness and vestibular dysfunction is a genetic disease affecting the nervous system. The clinical signs of this pathology are deafness, head tilt, circular movements and lack of coordination of the limbs as well as abnormal eye movements. The first symptoms (deafness) usually appear at the age of 3 weeks.

Congenital deafness in Rottweilers is a genetic disorder causing bilateral hearing loss from the first weeks of life. Affected puppies show profound deafness, without other apparent clinical signs.

This condition is associated with a mutation in the LOXHD1 gene, which plays a key role in the function of the cochlear hair cells.

Progressive retinal atrophy is characterised by the relatively early loss of cone photoreceptors while maintaining rod functionality. The first clinical signs appear around the age of 1 to 2 years, progressing to complete blindness.

Neonatal ataxia, also known as Bandera syndrome, is caused by a genetic mutation that alters the part of the nervous system that controls coordination and movement. Symptoms of neonatal ataxia include falling and inability to walk.

This test is also recommended for Havanese as part of the breeding program established by the Flemish government (see official program).

Locus I determines a dilution of the pheomelanin pigments (red or yellow pigment), resulting in a dilution of the fawn coat to cream, sand or white depending on the breed. The mutation does not affect the eumelanin pigments and therefore has no impact on the black or brown coat.

Centronuclear myopathy is a condition characterised by a generalised loss of tone, muscle control, exercise intolerance and clumsy gait. This myopathy usually manifests itself in puppies at the age of 2-5 months.

This test is also recommended for Labradoodle as part of the breeding program established by the Flemish government (see official program).