Search results for: 'DOG-PRA-PRCD'

Progressive retinal atrophy is an inherited eye disease characterized by bilateral degeneration of the photoreceptor cells of the retina resulting in progressive vision loss leading to total blindness. Other mutations can cause progressive retinal atrophy. 

Footpad hyperkeratosis is a genetic disease causing a proliferation of epidermal cells. The symptoms of this pathology are thickening and hardening of the pads of all four paws. The first clinical signs usually appear during the first year of life.

Mitochondrial fission encephalopathy is a genetic disease of the nervous system. Bullmastiffs with MFE show a variety of symptoms such as ataxia, visual impairment, progressive gait abnormalities and behavioral abnormalities. The first clinical signs are usually observed around 6 months of age.

Puppies with dry eye/curly coat syndrome have keratoconjunctivitis sicca in the eyes, a curly coat, and are generally smaller than their peers. The footpads are hyperkeratinised with abnormal claw growth.

L'insuffisance d'Adhérence Leucocytaire est une anomalie du système immunitaire. En raison de la mutation, les leucocytes ne détruisent pas les bactéries et les virus conduisant à la mort des chiots atteints.

This cardiomyopathy leads to death without apparent cause at around 6-8 weeks of age in the Belgian Shepherd. Symptoms of this condition vary from individual to individual and include: vomiting, dyspnoea, enlarged heart, difficulty in locomotion, tremors.

Congenital myasthenic syndrome is caused by a malfunction in the transmission of nerve signals to the muscle, with symptoms usually appearing between 6 and 12 weeks of age. Affected puppies show generalised skeletal muscle weakness and fatigue, usually induced by exercise.

Episodic falling syndrome is a neurological disorder in which episodes are triggered by exercise, stress or excitement and are characterised by stiffness of the thoracic and pelvic limbs. Symptoms vary from individual to individual.

Cleft lip with or without cleft palate is a genetic defect in craniofacial development causing communication between the mouth and nose. The most common symptoms are choking, coughing and difficulty swallowing. Syndactyly (fusion of fingers) may also be observed.

Cerebellar ataxia (NCL-A) is a genetic defect characterised by the accumulation of lipofuscin in the nervous system resulting in balance disorders, ambulation and uncontrolled muscle contractions. This test is licensed from INRA / ENVA.