Search results for: 'DOG-PRA-PRCD'

Junctional epidermolysis bullosa (JEB) is a recessive genetic disease of the skin and mucous membranes in which the epidermal layer is separated from the skin.

Factor VII deficiency is a genetic disorder affecting blood clotting. Symptoms are related to mild blood clotting disorders such as bleeding and bruising.

Gangliosidosis is a genetic defect that causes the storage of GM1 gangliosides in various tissues. The clinical signs of the disease are progressive neurological dysfunction and growth retardation.

Familial nephropathy is a kidney disease with progressive destruction of both kidneys. The first symptoms are excessive water consumption, weight loss, reduced appetite and vomiting.

Cerebellar abiotrophy is a neurodegenerative disease. Affected puppies show a variety of symptoms including loss of balance and an asymmetric gait with an inability to regulate speed and amplitude of movement. 

Centronuclear myopathy is a genetic disease affecting the muscles and characterized by progressive muscle atrophy and exercise intolerance. The first clinical signs appear around 6 months of age.

Cyclic neutropenia is a stem cell disease resulting in cyclic variation in the number of circulating neutrophils. The clinical signs of cyclic neutropenia are fever, diarrhoea, joint pain and respiratory, eye and skin infections. 

Von Willebrand disease is a condition that causes excessive bleeding due to a lack or reduced level of von Willebrand factor (vWF), a blood clotting protein. 

Autoinflammatory Shar-Pei Disease (AISD) is a genetic disorder characterized by recurrent episodes of fever and inflammation with no known cause. The most common symptoms are fever, arthritis, vesicular hyaluronosis, otitis and amyloidosis.

Pyruvate dehydrogenase is an important enzyme for the production of energy by cells. Pyruvate dehydrogenase deficiency is therefore characterised by an intolerance to effort and lactic acidosis. Neurological complications are possible.