Search results for: 'DOG-PRA-PRCD'

Muscle hypertrophy in whippets, sometimes called “bully,” is a genetic trait that results in a highly developed musculature, particularly in the neck and limbs.
Affected dogs have a broad chest and generally do not conform to the breed standard, which favors a slim body, long neck, and pointed muzzle.
Whippets carrying a single copy of the mutation show moderate muscular development but are often faster than dogs homozygous for the normal allele, providing a performance advantage.

Spinocerebellar ataxia (SCA or SAMS) is a genetic disease of the nervous system. Affected dogs present the first signs of ataxia around the age of 3 to 6 months. The symptoms of this pathology are a loss of balance, a progressive lack of coordination until the total loss of mobility. Another test for late-onset spinocerebellar ataxia is available. For more information, consult the DOG-LOA test.

Dogs with POAG have elevated intraocular pressure that can lead to vision loss. Symptoms of this condition include eye pain, excessive blinking and tearing.

Dogs with POAG have elevated intraocular pressure that can lead to vision loss. Symptoms of this condition include eye pain, excessive blinking and tearing.

Complement factor C3 deficiency in dogs is a condition that leads to immune system failure. This condition makes affected dogs more susceptible to multiple and recurrent bacterial infections, as well as certain kidney diseases of immune origin. The gene involved in this pathology is the C3 gene, with a specific mutation identified as c.2136delC. The frequency of carriers of this mutation is approximately 1%, and symptoms can appear from a very young age.

Thrombopathia is a genetic disease that affects platelet function. In thrombopathia, platelets are unable to stick together properly and therefore cannot clot normally. The most common symptoms of this condition are recurrent nosebleeds and excessive bleeding from the gums and bruising. Internal bleeding and black or red stools may also be observed. Although dogs with this condition are at risk for spontaneous bleeding and internal bleeding, affected dogs may not be identified until surgery is performed or trauma occurs.

 

Skeletal dysplasia type 3 is an inherited condition described notably in the Vizsla, associated with a variant in the PCYT1A gene. It primarily results in reduced shoulder height in homozygous dogs, with notable individual variability. The skeletal abnormalities mainly affect the limbs, with shortened, thickened, and deformed bones visible on imaging. Despite these structural changes, affected dogs do not consistently show obvious clinical signs in the short term. However, long-term monitoring is recommended to assess potential orthopedic consequences with age.

Benign familial juvenile epilepsy is a disease in which clinical signs appear between 5 and 12 weeks of age. Affected dogs exhibit convulsions characterised by generalised tremors, ataxia and stiffness.

Dogs with POAG have elevated intraocular pressure leading to loss of vision and usually to lens luxation (PLL). The first symptoms usually appear between 4 and 6 years of age.

Cataracts are one of the leading causes of blindness in dogs. This test highlights a mutation in the HSF4 gene that is considered a risk factor for the development of cataracts.