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This panel includes the specific tests to be performed for the Chihuahua: curly coat (DOG-CUR), intervertebral disc disease (DOG-IVDD), neuronal ceroid lipofuscinosis type 7 (DOG-NCL7) and progressive rod-cone degeneration (DOG-PRA-PRCD).

This profile includes the specific tests to be performed for Belgian Shepherds: spongy degeneration with cerebellar ataxia type 1 (DOG-SDCA1), spongy degeneration with cerebellar ataxia type 2 (DOG-SDCA2), X-linked hypohidrotic ectodermal dysplasia (DOG-XHED) and cardiomyopathy and juvenile mortality (DOG-CMJM-BB).

The melanocortin-1 receptor (MC1R) gene, also called extension (E), controls the production of black and red pigment in cattle.

Rod-cone dysplasia 4 is one of several forms of progressive retinal atrophy (PRA). This mutation leads to the late onset of PRA, with blindness occurring after 7 years of age.

This panel includes the specific tests to be performed for the German Shepherd Dog: achromatopsia (DOG-ACHMB), Scott syndrome (DOG-CSS), coat length (DOG-LH), multidrug resistance (DOG-MDR1), mucopolysaccharidosis VII (DOG-MPS7), dwarfism (DOG-NAN), renal cystadenocarcinoma and nodular dermatofibrosis (DOG-RCND) and X-linked hypohidrotic ectodermal dysplasia (DOG-XHED).

Progressive retinal atrophy causes blindness due to the destruction of the photoreceptors in the retina. The loss of vision begins at the age of 7 months and gradually declines until it is almost complete by the age of 3 to 5 years.

This pack includes the recommended tests defined by the Flemish breeding program for Chihuahua: Von Willebrand disease type 1 (DOG-VWD1), Neuronal ceroid lipofuscinosis type 7 (DOG-NCL7) and Coat color merle (DOG-LOCUS-M).

The Flemish breeding program also requires the tests included in our DOG-CHI-VL pack.

Hypocatalasia (or acatalasemia) is a rare genetic disorder caused by a mutation in the CAT gene, leading to a severe deficiency of catalase. This enzyme normally protects tissues against oxidative stress. The c.979G>A (p.Ala327Thr) mutation was first identified in a Beagle colony and subsequently detected in pet Beagles. A homozygous dog notably developed oral cavity gangrene with tooth loss at a young age. The disease may remain clinically silent for a long time, which highlights the importance of genetic screening in breeding dogs.
This test is also recommended for the Basset Hound as part of the Flemish government breeding program (see the official program).

Neonatal encephalopathy is a malformation of the cerebellum seen in poodles. Affected puppies are small at birth and do not develop normally. At the age of about 3 weeks, weakness, ataxia, tremors are observed. Affected puppies do not interact with the mother or other members of the litter and react slowly to external stimuli. They usually die or are euthanised before 7 weeks of age.

The PPARD gene is involved in mechanisms related to energy metabolism, fat utilisation and muscular endurance. In racing pigeons, a recent study suggests that certain variations in this gene may be linked to race performance, particularly return speed and ranking coefficient. The CC genotype for the PPARD c.*271C>T marker is the one that stands out most favourably in the study, notably because it was observed in pigeons taking part in a larger number of races. This test can therefore provide complementary information to guide the selection of breeding birds, without replacing the assessment of the pigeon, its lineage, training and actual racing results.