Search results for: 'DOG-PRA-PRCD'

Progressive retinal atrophy (IFT122) is a genetic disease of the Finnish Lapphund that causes gradual degeneration of the retina, primarily affecting night vision. Early signs include night blindness and diffuse tapetal hyperreflectivity, detectable through an ophthalmologic examination. The disease generally progresses slowly, and some dogs may retain partial vision at an advanced age.

This test is also recommended for the Finnish Lapphund as part of the breeding program implemented by the Flemish government (see official program).

Cone-rod dystrophy 1 is a form of progressive retinal atrophy characterised by an early, severe and rapidly progressive loss of cone function accompanied by a progressive loss of rods.

Cone-rod dystrophy 2 is a form of progressive retinal atrophy characterised by an early, severe and rapidly progressive loss of cone function accompanied by a progressive loss of rods.

Progressive retinal atrophy (PRA1) is a genetic disease characterised by the degeneration of rod photoreceptors in the eye. The first symptoms of vision loss appear between the ages of 4 and 6.

Von Willebrand disease is a condition that causes excessive bleeding due to a deficiency or reduced levels of von Willebrand factor (vWF), a blood clotting protein.

This mutation is found in the Chinese Crested dog, but homozygous dogs do not appear to show clinical signs of bleeding disorders.

Gangliosidosis is a genetic defect that causes the storage of GM1 gangliosides in various tissues. The clinical signs of the disease are progressive neurological dysfunction and growth retardation

Neuronal ceroid lipofuscinosis is a hereditary neurodegenerative disease, with the first symptoms typically appearing around the age of 6. It manifests as cognitive disorders, anxiety, seizures, loss of coordination, sensory impairments, and behavioral changes. Dogs affected by this condition are generally euthanized.

This test is also recommended for the Jack Russell Terrier as part of the breeding program established by the Flemish government (see official program).

Degenerative myelopathy is a neurodegenerative disease that progresses slowly and has a late onset (8 years or more). The initial clinical sign is characterised by hind limb ataxia. As the disease progresses, the frequently observed asymmetric weakness rises to affect the thoracic limbs, leading to paraplegia.

Multiple system degeneration usually begins between 9 weeks and 6 months of age. The first signs include mild tremors and stiffness of the forelimbs.
Within 3 to 4 months, symptoms worsen, with severe ataxia, spasticity, an unsteady gait, and delayed postural reactions. The disease progresses to immobility and inability to stand, often leading to euthanasia between 1 and 2 years of age.

Neuronal ceroid lipofuscinosis is a genetic defect characterised by cognitive impairment, blindness and anxiety.