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Myotubular myopathy type 1, also known as X-linked myotubular myopathy, is a genetic disease of the skeletal muscles. Clinical signs include hypotonia, muscle atrophy and breathing difficulties. The disease is transmitted in an X-linked recessive manner, so males carrying the mutation will all be affected. However, only females with 2 copies of the mutated allele will be affected.

This package includes the mandatory tests defined by the Flemish breeding program for American Staffordshire Terrier: degenerative myelopathy type 2 (DOG-DM2), neuronal ceroid lipofuscinosis 4A (DOG-NCLA), progressive retinal atrophy type 4 (DOG-PRA-CRD4) and progressive retinal atrophy type 1 (DOG-PRA-RCD1).

The Flemish breeding program also recommends the tests included in our DOG-AMSTAFF-VL+ pack.

Multiple system degeneration usually begins between 9 weeks and 6 months of age. The first signs include mild tremors and stiffness of the forelimbs.
Within 3 to 4 months, symptoms worsen, with severe ataxia, spasticity, an unsteady gait, and delayed postural reactions. The disease progresses to immobility and inability to stand, often leading to euthanasia between 1 and 2 years of age.

This package includes the mandatory tests defined by the Flemish breeding program for Australian cattle dog: Degenerative myelopathy 2 (DOG-DM2), Neuronal ceroid lipofuscinosis type 12 (DOG-NCL12-ACD), Neuronal ceroid lipofuscinosis type 5 (DOG-NCL5), Primary lens luxation (DOG-PLL), Progressive rod-cone degeneration (DOG-PRA-PRCD). The Flemish breeding program also recommends the tests included in our package DOG-AC-VL+.

This package includes the mandatory tests defined by the Flemish breeding program for English Springer Spaniel: Acral Mutilation Syndrome (DOG-AMS), Progressive retinal atrophy 4 (CORD1) (DOG-PRA-CRD4), Degenerative myelopathy 2 (DOG-DM2), la déficience en phosphofructokinase (DOG-PFKM) and Paradoxical pseudomyotonia (SLC7A10) (DOG-PPM). The Flemish breeding program also recommends the tests included in our package DOG-ESS-VL+.

This package includes the mandatory tests defined by the Flemish breeding program for Labradoodle: Degenerative myelopathy 2 (DOG-DM2), Centronuclear myopathy (DOG-CNM), Exercise-induced collapse (DOG-EIC), Hereditary nasal parakeratosis (DOG-HNPK), Progressive rod-cone degeneration (DOG-PRA-PRCD), Stargardt disease (DOG-STGD) and Von Willebrand disease type 1 (DOG-VWD1). The Flemish breeding program also recommends the tests included in our package DOG-DOODLE-VL+.

This pack includes the recommended tests defined by the Flemish breeding program for German Shorthaired Pointer: Achromatopsia (CNGB3) (DOG-ACHM3), Acral Mutilation Syndrome (DOG-AMS), ichtyosis type 1 (DOG-ICHGR-1), Progressive rod-cone degeneration (DOG-PRA-PRCD), Stargardt disease (DOG-STGD) and Von Willebrand disease type 2 (DOG-VWD2-BA). The Flemish breeding program also makes the tests included in our package mandatory DOG-BRQALLD-VL.

Hypomyelination, also known as Shaking pup syndrome, is a disorder of the nervous system caused by a defect in the myelination of the spinal cord. Affected dogs show tremors, walking difficulties, balance and coordination problems. This disease is transmitted in an X-linked recessive manner, so males carrying the mutation will all be affected. However, only females with 2 copies of the mutated allele will be affected.

The locus D or dilution refers to a mutation in the MLPH gene that causes a diluted coat colour. This mutation dilutes black to blue, chocolate to lilac and yellow to champagne. The mutation tested is the d^2 mutation and is specific to the Chow Chow, Sloughi and Thai Ridgeback breeds. For the other breeds, the test to be performed is the DOG-LOCUS-D test.

Lethal acrodermatitis is a genetic disease of the immune system. The clinical signs are skin lesions on the paws and muzzle, leading to secondary infections. In addition, the lesions cause hyperkeratosis of the pads and deformation of the nails. Affected puppies also suffer from diarrhea, bronchopneumonia and retarded growth. The first symptoms appear quickly after birth. Affected puppies usually die before 2 years of age or are euthanized.