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Dogs with POAG have elevated intraocular pressure that can lead to vision loss. Symptoms of this condition include eye pain, excessive blinking and tearing.

Dogs with POAG have elevated intraocular pressure leading to loss of vision and usually to lens luxation (PLL). The first symptoms usually appear between 4 and 6 years of age.

Dogs with POAG have elevated intraocular pressure that can lead to vision loss. Symptoms of this condition include eye pain, excessive blinking and tearing.

This package includes the mandatory tests defined by the Flemish breeding program for Beagle: Exercise-induced collapse (DOG-EIC), Congenital myasthenia (CMS-CHRNE), Pyruvate kinase deficiency (PKDEFB), Primary open-angle glaucoma (POAG-B) and Progressive retinal atrophy (PRA-PRCD). The Flemish breeding program also makes the tests included in our package mandatory DOG-BEAGLE-VL.

Hypocatalasia (or acatalasemia) is a rare genetic disorder caused by a mutation in the CAT gene, leading to a severe deficiency of catalase. This enzyme normally protects tissues against oxidative stress. The c.979G>A (p.Ala327Thr) mutation was first identified in a Beagle colony and subsequently detected in pet Beagles. A homozygous dog notably developed oral cavity gangrene with tooth loss at a young age. The disease may remain clinically silent for a long time, which highlights the importance of genetic screening in breeding dogs.
This test is also recommended for the Basset Hound as part of the Flemish government breeding program (see the official program).

Golden Retriever muscular dystrophy is a homologue of Duchenne muscular dystrophy in humans. Affected dogs develop clinical signs at 8 to 10 weeks of age. Symptoms include a shuffling gait, inability to fully open the jaw, difficulty eating, curvature of the spine and ribs, resulting in a squatted posture. he disease is transmitted in an X-linked recessive manner, so males carrying the mutation will all be affected. However, only females with 2 copies of the mutated allele will be affected.

Craniomandibular osteopathy (CMO) is a bone disease affecting young dogs, usually between 4 and 8 months of age.
It appears as swelling of the jaw, pain, difficulty opening the mouth, fever, and loss of appetite. Excessive bone growth mainly affects the mandible and skull, and sometimes the long bones.
The mutation may be present without causing visible symptoms, due to its variable expression and incomplete penetrance.

This test is also recommended for the American Staffordshire Terrier as part of the breeding program of the Flemish government (see the official program).