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Ichthyosis type 2 is a skin condition caused by keratin dysfunction. The skin of affected dogs is dry, thick, scaly with large skin scales. 

In addition to the genetic test available for this form, a specific test is also available for ichthyosis type 1.

Polyneuropathy type 1 (LNP21) is a progressive neuromuscular disease characterised by generalised weakness, hypotonia, laryngeal paralysis and muscle atrophy, particularly of the hind limbs. The age of onset of symptoms can vary between 1 and 11 years.

Polyneuropathy type 1 (LNP1) is a progressive neuromuscular disease characterised by generalised weakness, hypotonia, laryngeal paralysis and muscle atrophy, particularly of the hind limbs. The age of onset of symptoms can vary between 1 and 11 years.

Landseers with Ullrich-type muscular dystrophy show general muscle weakness. The first symptoms appear in the first months of life, and these dogs are euthanised or die before the age of two.

Hypocatalasia (or acatalasemia) is a rare genetic disorder caused by a mutation in the CAT gene, leading to a severe deficiency of catalase. This enzyme normally protects tissues against oxidative stress. The c.979G>A (p.Ala327Thr) mutation was first identified in a Beagle colony and subsequently detected in pet Beagles. A homozygous dog notably developed oral cavity gangrene with tooth loss at a young age. The disease may remain clinically silent for a long time, which highlights the importance of genetic screening in breeding dogs.
This test is also recommended for the Basset Hound as part of the Flemish government breeding program (see the official program).

Cystinuria is a disorder that interferes with the proper reabsorption of cystine (an amino acid) in the kidneys leading to the formation of cystine crystals in the urine. Affected dogs have cystine crystals in the kidneys and/or bladder. 

Cystinuria is caused by a lack of renal reabsorption of the amino acid cystine. This excess of urinary cystine causes crystals to form, which can lead to the formation of stones in the kidney and/or bladder. Cats with cystinuria suffer from repeated inflammation of the urinary tract.

Narcolepsy is a genetic disorder caused by a mutation in the orexin receptor. Affected dogs are sleepy and cannot stay awake for long periods. The first signs appear between 4 weeks and 6 months. Narcolepsy is not life-threatening.

Cerebral neuronal lipofuscinosis type 8 (NCL8) is a hereditary neurodegenerative disease observed in certain breeds such as the German Shorthaired Pointer and the Australian Shepherd. Puppies develop normally until 12–14 months of age, after which signs of neurological degeneration appear, including visual impairment, repetitive behaviors, and decreased responsiveness to commands. The disease progresses to blindness, ataxia, and loss of motor function in the limbs, accompanied by frequent epileptic seizures. Due to the severity of symptoms and rapid progression, affected animals are often euthanized before 27 months of age.

Neuronal ceroid lipofuscinosis is a genetic defect characterised by cognitive impairment, blindness and anxiety.